Nolvadex, stiprus nesteroidinis vaistas, pasi\u017eymi puikiomis antiestrogenin\u0117mis savyb\u0117mis, nes jungiasi prie estrogen\u0173 receptori\u0173 ir veiksmingai slopina estrogen\u0173 poveik\u012f. Jis pirmiausia skirtas tam tikr\u0173 tip\u0173 kr\u016bties v\u0117\u017eiui gydyti tiek moterims, tiek vyrams. Be to, jis tarnauja kaip kr\u016bties v\u0117\u017eio prevencin\u0117 priemon\u0117 moterims, sergan\u010dioms didel\u0117s rizikos latak\u0173 karcinoma in situ. T\u0119siant tyrimus tiriamas jo veiksmingumas kit\u0173 form\u0173 kr\u016bties v\u0117\u017eio atveju.<\/p>
Nolvadex, skirtas metastazavusiam kr\u016bties v\u0117\u017eiui gydyti, yra veiksmingas tiek moterims prie\u0161 menopauz\u0119, tiek moterims po menopauz\u0117s, tiek vyrams. \u0160is preparatas yra prana\u0161esnis u\u017e chirurgin\u0119 operacij\u0105 ar spinduliavim\u0105, ypa\u010d naudingas pacientams, kuri\u0173 navikas turi teigiam\u0173 estrogen\u0173 receptori\u0173. Jis taip pat vartojamas kaip pagalbin\u0117 terapija po kr\u016bties v\u0117\u017eio operacijos.<\/p>
Nolvadex galima \u012fsigyti 10\/20 mg tab table\u010di\u0173 ir 10 mg tirpalo pavidalu, standartin\u0117 paros doz\u0117 yra 20 mg. Lengvai pasisavinamas, j\u012f galima vartoti valgant arba nevalgius. Sergantiesiems kr\u016bties v\u0117\u017eiu rekomenduojamos doz\u0117s svyruoja nuo 20 iki 40 mg per par\u0105, paprastai padalytos \u012f 1-3 dozes. Kult\u016bristai da\u017enai gydym\u0105 pradeda nuo 20 mg per par\u0105, o kai kurie padidina iki 30 mg per par\u0105. Paprastai jo nereik\u0117t\u0173 vartoti ilgiau kaip 5 metus.<\/p>
Nors Nolvadex neturi tiesioginio anabolinio ar androgeninio poveikio, jis daro antrin\u012f poveik\u012f per estrogen\u0173 receptori\u0173 blokad\u0105. Inhibuodamas \u0161iuos receptorius pagumburyje, jis signalizuoja apie lytini\u0173 hormon\u0173 tr\u016bkum\u0105, sukeldamas gonadotropin\u0173 (LH ir FSH) padid\u0117jim\u0105 ir taip sustiprindamas testosterono sintez\u0119. \u0160is testosterono padid\u0117jimas susij\u0119s su anaboliniu ir androgeniniu poveikiu, priskiriamu Nolvadex.<\/p>
Daugelis kult\u016brist\u0173 Nolvadex vartoja po anabolini\u0173 steroid\u0173 ciklo, nes jis neutralizuoja steroid\u0173 sukelt\u0105 testosterono slopinim\u0105. Nors Nolvadex ir Arimidex vartojimas skiriasi, abu preparatai veikia pana\u0161iai. Blokuodamas estrogen\u0173 aktyvum\u0105, Nolvadex padeda i\u0161vengti ginekomastijos ir vandens susilaikymo be didelio svorio prieaugio.<\/p>
Nolvadex da\u017enai skiriamas moterims, kovojan\u010dioms su metastazavusiu kr\u016bties v\u0117\u017eiu. Ta\u010diau bet kuri pacient\u0117, vartojanti \u0161\u012f vaist\u0105, tiek medicininiais, tiek kult\u016brizmo tikslais, tur\u0117t\u0173 b\u016bti pri\u017ei\u016brima gydytojo. Moterims patariama steb\u0117ti, ar neatsiranda galimas \u0161alutinis poveikis, pvz:<\/p>
Vartojan\u010dioms Nolvadex b\u016btina reguliariai tikrintis kr\u016btis pas sveikatos prie\u017ei\u016bros specialistus. Be to, kult\u016brist\u0117s turi atkreipti d\u0117mes\u012f \u012f tai, kad hormonin\u0117s kontraceptin\u0117s priemon\u0117s gali b\u016bti neveiksmingos vartojant
Nolvadex.<\/p>
Apskritai Nolvadex laikomas saugiu, nustatyta, kad tik 1-3% pacient\u0173 patiria reik\u0161ming\u0105 \u0161alutin\u012f poveik\u012f. Da\u017eniausiai pasitaikan\u010dios reakcijos abiej\u0173 ly\u010di\u0173 pacientams yra \u0161ios:<\/p>
Dauguma \u0161alutini\u0173 poveiki\u0173 paprastai i\u0161nyksta nutraukus vaisto vartojim\u0105.<\/p>
\u017dinokite apie galim\u0105 rizik\u0105, pavyzd\u017eiui, hiperkalcemij\u0105 ir retus gimdos v\u0117\u017eio atvejus, susijusius su Nolvadex. Kitas susir\u016bpinim\u0105 keliantis dalykas yra kraujo kre\u0161\u0117jimas, nes kyla embolijos rizika. Retos komplikacijos taip pat gali b\u016bti kepen\u0173 v\u0117\u017eys ir reg\u0117jimo poky\u010diai.<\/p>
Nolvadex paprastai yra saugus, perdozavimo atvej\u0173 nepasteb\u0117ta. Simptomai gali pasireik\u0161ti tik pra\u0117jus 4-6 dienoms po pavartojimo, tod\u0117l gali atsirasti drebulys, netvirta eisena ar nereguliarus \u0161irdies ritmas. Gydymas paprastai apima palaikom\u0105j\u012f gydym\u0105, nuolatinio toksinio poveikio nesitikima.<\/p>
\u0160\u012f vaist\u0105 tikrina daugyb\u0117 sporto organizacij\u0173. Nors Nolvadex teis\u0117tai skiriamas moterims, vyrai, turintys Nolvadex, yra diskvalifikuojami i\u0161 var\u017eyb\u0173. \u0160lapime jo galima aptikti iki 3-4 savai\u010di\u0173 po vartojimo.<\/p>
Nolvadex kaina gali skirtis, vidutini\u0161kai $1,50-$2,00 u\u017e tablet\u0119. Generin\u0117s Azijos alternatyvos yra ekonomi\u0161kai naudingesn\u0117s, ta\u010diau gali nukent\u0117ti kokyb\u0117 ir grynumas. Iki \u0161iol neprane\u0161ta apie padirbtus Nolvadex preparatus.<\/p>","protected":false},"excerpt":{"rendered":"
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