Nolvadex, kl\u012bniski paz\u012bstams k\u0101 tamoksif\u0113ns, ir nestero\u012bds l\u012bdzeklis, kam piem\u012bt sp\u0113c\u012bgas antiestrog\u0113nu \u012bpa\u0161\u012bbas. Saistoties ar estrog\u0113nu receptoriem, tas efekt\u012bvi blo\u0137\u0113 estrog\u0113nu iedarb\u012bbu. \u0160is medikaments ir b\u016btisks noteiktu kr\u016bts v\u0113\u017ea veidu \u0101rst\u0113\u0161an\u0101 gan sieviet\u0113m, gan v\u012brie\u0161iem. Turkl\u0101t Nolvadex ir profilaktiska noz\u012bme sieviet\u0113m ar paaugstin\u0101tu risku, ko rada dukt\u0101l\u0101 karcinoma in situ. Pa\u0161laik tiek veikti p\u0113t\u012bjumi, kuros tiek p\u0113t\u012bta t\u0101 efektivit\u0101te citu kr\u016bts v\u0113\u017ea formu gad\u012bjum\u0101.<\/p>
Nolvadex ir indic\u0113ts metast\u0101tiska kr\u016bts v\u0113\u017ea \u0101rst\u0113\u0161anai abiem dzimumiem un \u012bpa\u0161i ieteicams sieviet\u0113m pirms menopauzes. Pacient\u0113m ar estrog\u0113nu receptoru pozit\u012bviem audz\u0113jiem tas ir v\u0113lam\u0101 alternat\u012bva oper\u0101cijai vai apstaro\u0161anai, un to lieto k\u0101 papildterapiju p\u0113c \u0137irur\u0123iskas iejauk\u0161an\u0101s kr\u016bts v\u0113\u017ea \u0101rst\u0113\u0161an\u0101.<\/p>
Nolvadex ir pieejams 10 mg un 20 mg tablet\u0113s, k\u0101 ar\u012b 10 mg \u0161\u0137\u012bdum\u0101. Standarta dienas deva ir 20 mg, kas tiek lietota iek\u0161\u0137\u012bgi, ar \u0113rtu uzs\u016bk\u0161anos neatkar\u012bgi no p\u0101rtikas uz\u0146em\u0161anas. Kr\u016bts v\u0113\u017ea pacient\u0113m dienas devas ir 20-40 mg, ide\u0101li sadal\u012btas 1-3 dev\u0101s. Bodybuilderi parasti s\u0101k ar 20 mg dien\u0101, da\u017ei palielina l\u012bdz 30 mg dien\u0101. Ilgsto\u0161a terapija ilg\u0101k par pieciem gadiem nav ieteicama.<\/p>
Lai gan Nolvadex nepiem\u012bt tie\u0161as anaboliskas vai androg\u0113nas \u012bpa\u0161\u012bbas, t\u0101 iedarb\u012bba izriet no estrog\u0113nu receptoru blok\u0101des. \u0160is meh\u0101nisms liek hipotal\u0101mam uztvert dzimumhormonu tr\u016bkumu, izraisot gonadotrop\u012bnu (LH un FSH) piepl\u016bdumu, t\u0101d\u0113j\u0101di palielinot testosterona ra\u017eo\u0161anu. \u0160\u012b palielin\u0101\u0161an\u0101s izraisa sekund\u0101ro anabolisko iedarb\u012bbu, kas saist\u012bta ar Nolvadex.
Bodybuilderi bie\u017ei lieto Nolvadex p\u0113canabola stero\u012bdu ciklu laik\u0101, lai neitraliz\u0113tu testosterona sint\u0113zes nom\u0101kumu, l\u012bdztekus alternat\u012bv\u0101m iesp\u0113j\u0101m, piem\u0113ram, Arimidex, lai ieg\u016btu l\u012bdz\u012bgu iedarb\u012bbu. T\u0101 estrog\u0113nu blo\u0137\u0113\u0161anas sp\u0113ja pal\u012bdz nov\u0113rst ginekomastiju un \u0161\u0137idruma aizturi, padarot Nolvadex par v\u0113rt\u012bgu l\u012bdzekli, lai saglab\u0101tu svara pieaugumu p\u0113c stero\u012bdu lieto\u0161anas.<\/p>
Nolvadex bie\u017ei izraksta sieviet\u0113m, kas c\u012bn\u0101s ar metast\u0101tisku kr\u016bts v\u0113zi. Ir \u013coti svar\u012bgi, lai sievietes, kas lieto \u0161\u012bs z\u0101les, uzraudz\u012btu vesel\u012bbas apr\u016bpes speci\u0101listi, \u012bpa\u0161i attiec\u012bb\u0101 uz \u0161\u0101d\u0101m iesp\u0113jam\u0101m blakuspar\u0101d\u012bb\u0101m:<\/p>
Vis\u0101m sieviet\u0113m, kuras lieto Nolvadex, ir \u013coti svar\u012bgi regul\u0101ri veikt kr\u016b\u0161u p\u0101rbaudes. Ir b\u016btiski atz\u012bm\u0113t, ka \u0161\u012bs z\u0101les var padar\u012bt neefekt\u012bvas kontracepcijas tabletes.<\/p>
Nolvadex tiek uzskat\u012bts par \u013coti dro\u0161u, jo noz\u012bm\u012bgas blakuspar\u0101d\u012bbas rodas maz\u0101k nek\u0101 1-3% lietot\u0101ju. Bie\u017e\u0101k zi\u0146ot\u0101s blakuspar\u0101d\u012bbas ir \u0161\u0101das:<\/p>
Liel\u0101k\u0101 da\u013ca blakuspar\u0101d\u012bbu izz\u016bd p\u0113c z\u0101\u013cu lieto\u0161anas p\u0101rtrauk\u0161anas.<\/p>
Nolvadex lietot\u0101jiem j\u0101zina par iesp\u0113jamo risku, piem\u0113ram, hiperkalci\u0113miju kr\u016bts v\u0113\u017ea pacient\u0113m neilgi p\u0113c lieto\u0161anas uzs\u0101k\u0161anas. Ir ar\u012b zi\u0146ojumi par iesp\u0113jamu dzemdes v\u0113zi saist\u012bb\u0101 ar Nolvadex. Turkl\u0101t z\u0101les var palielin\u0101t asins recek\u013cu veido\u0161an\u0101s risku, kas var izrais\u012bt plau\u0161u emboliju. Ir dokument\u0113ti reti aknu v\u0113\u017ea un redzes izmai\u0146u gad\u012bjumi.<\/p>
Nolvadex parasti ir dro\u0161s, nav zi\u0146ojumu par p\u0101rdoz\u0113\u0161anu. Lietojot p\u0101rm\u0113r\u012bgu table\u0161u daudzumu, simptomi var par\u0101d\u012bties tikai p\u0113c 4-6 dien\u0101m, iesp\u0113jams, izraisot tr\u012bci, instabilpumu, reiboni vai sirdsdarb\u012bbas trauc\u0113jumus. Ieteicama atbalsto\u0161a \u0101rst\u0113\u0161ana, jo nav zin\u0101ma ilgsto\u0161a toksicit\u0101te.<\/p>
Daudzas sporta organiz\u0101cijas akt\u012bvi test\u0113 Nolvadex. V\u012brie\u0161iem, kuri ir pozit\u012bvi test\u0113ti uz \u0161o medikamentu, var tikt diskvalific\u0113ti no sporta sacens\u012bb\u0101m, neraugoties uz to, ka sieviet\u0113m ir likum\u012bgi izrakst\u012btas receptes. Prepar\u0101tu var atkl\u0101t ur\u012bn\u0101 3-4 ned\u0113\u013cas p\u0113c lieto\u0161anas.<\/p>
Nolvadex ir pieejams, bet cena at\u0161\u0137iras, vid\u0113ji $1,50-$2,00 par tableti. Ir pieejamas pieejam\u0101kas \u0123en\u0113risko z\u0101\u013cu alternat\u012bvas no \u0100zijas, lai gan to kvalit\u0101te var b\u016bt ap\u0161aub\u0101ma, un viltots Nolvadex v\u0113l nav par\u0101d\u012bjies.<\/p>","protected":false},"excerpt":{"rendered":"
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