Ajanta Kamagra Chewable 4 tabs (100 mg/tab)

Sildenafil

Sildenafil, commonly known as Viagra, is a renowned medication classified under phosphodiesterase type 5 (PDE5) inhibitors.

Mechanism of Action

• Sildenafil functions by inhibiting the enzyme phosphodiesterase type 5 (PDE5), responsible for reducing cyclic guanosine monophosphate (cGMP) levels. During sexual arousal, nitric oxide (NO) promotes elevated cGMP levels, leading to the relaxation of smooth muscles in blood vessels and enhanced blood circulation to the penis.
• This process facilitates the achievement and maintenance of an erection.

Indications

• The primary indication for sildenafil is the treatment of erectile dysfunction in men.
• It is also utilized in treating arterial hypertension under the brand name Revatio.

Onset of Action

• Sildenafil typically starts to take effect within 30 minutes post-administration, although it may take up to one hour for some users.

Duration of Action

• The impact of sildenafil generally lasts between 4 to 5 hours, providing ample time for achieving and sustaining an erection.

Dosage

• The recommended initial dosage of sildenafil is 50 mg, adjustable based on individual reactions and requirements.
• This medication should be ingested about 30 minutes to 1 hour before intended sexual activity.

Side Effects

• Typical side effects associated with sildenafil include headache, facial flushing, dyspepsia (which can manifest as nausea or diarrhea), visual disturbances (e.g., blurred vision, altered color perception), elevated blood pressure, and, in rare cases, hearing loss or alterations in auditory function.

Contraindications

• It is critical not to combine sildenafil with nitrates (like nitroglycerin) due to the risk of a significant drop in blood pressure. This medication is contraindicated for those with severe heart conditions, recent myocardial infarction, or stroke.