LA Pharma Sildenafil 10 tabs (100 mg/tab)

Sildenafil

Sildenafil, commonly known by its brand name Viagra, is a member of the phosphodiesterase type 5 (PDE5) inhibitors class of medications.

Below are key features of Sildenafil:

Mechanism of Action

• Sildenafil inhibits the enzyme phosphodiesterase type 5 (PDE5), preventing the breakdown of cyclic guanosine monophosphate (cGMP). Increased levels of nitric oxide (NO) during sexual arousal improve blood flow to the penis, promoting erections.
• This results in the ability to achieve and sustain an erection.

Indications

• Sildenafil is primarily indicated for the treatment of erectile dysfunction in men.
• It is also utilized for managing arterial hypertension under the name Revatio.

Onset of Action

• The onset of Sildenafil is typically rapid, taking effect within approximately 30 minutes to 1 hour post-dose.

Duration of Action

• Effects generally last between 4 to 5 hours, enabling the achievement and maintenance of an erection.

Dosage

• Initial dosing usually starts at 50 mg, adjustable to individual response and requirements.
• Dose should be administered roughly 30 minutes to 1 hour prior to planned sexual activity.

Side Effects

• Common adverse effects may include headaches, facial flushing, dyspepsia (e.g., nausea, diarrhea), visual disturbances (e.g., blurred vision, altered color perception), elevated blood pressure, and infrequently, hearing impairments.

Contraindications

• Concurrent use of nitrates (e.g., nitroglycerin) is contraindicated due to risk of significant hypotension.
• Patients with severe cardiovascular conditions, recent myocardial infarction, or stroke should avoid Sildenafil.