Pfizer Viagra 4 tabs (100 mg/tab)

Sildenafil

Viagra is a leading medication classified as a phosphodiesterase type 5 (PDE5) inhibitor, effectively addressing erectile dysfunction.

Mechanism of Action

• Phosphodiesterase type 5 inhibition by sildenafil raises cyclic guanosine monophosphate (cGMP) levels in penile tissues. This process is initiated by nitric oxide (NO) release during sexual stimulation, facilitating muscle relaxation and enhancing blood flow to the penis.
• This mechanism supports the achievement and maintenance of an erection.

Indications

• Sildenafil is primarily indicated for treating erectile dysfunction in men.
• Additionally, it may be utilized for managing arterial hypertension under the trade name Revatio.

Onset of Action

• The onset of sildenafil’s effects is typically rapid, beginning about 30 minutes after ingestion; however, some individuals may experience a delay of up to 1 hour.

Duration of Action

• The action of sildenafil usually persists for 4 to 5 hours, allowing sufficient time to achieve and sustain an erection.

Dosage

• The recommended initial dosage is 50 mg, adjustable based on individual efficacy and tolerance.
• It is advisable to consume the dose approximately 30 minutes to 1 hour prior to anticipated sexual activity.

Side Effects

• Common side effects may encompass headache, facial flushing, indigestion (including nausea and diarrhea), vision alterations (such as blurred or color vision changes), elevated blood pressure, and in rare instances, hearing impairments.

Contraindications

• Sildenafil is contraindicated for use with nitrates (e.g., nitroglycerin) due to the risk of significant hypotension. It is also not recommended for individuals with severe cardiovascular conditions or recent myocardial infarction or stroke.