Sunrise Extra Super Tadarise 10 tabs (40 + 60 mg/tab)

Tadalafil – Cialis

Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor, primarily marketed as Cialis for treating erectile dysfunction and as Adcirca for pulmonary arterial hypertension management.

Mechanism of Action

• Tadalafil inhibits PDE5, preventing the breakdown of cyclic guanosine monophosphate (cGMP).
• With sexual stimulation, nitric oxide (NO) release elevates cGMP levels.
• This promotes relaxation in the blood vessels, enhancing blood flow to the penis for an erection.

Indications

• Used mainly for erectile dysfunction in men.
• Also effective for treating benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension.

Onset of Action

• Rapid onset, typically within 30 minutes to 1 hour post-ingestion.

Duration of Action

• Lasts up to 36 hours, often referred to as the “weekend pill.”
• Men can maintain an erection during this duration with sexual arousal.

Dosage

• For erectile dysfunction, a dose of 10 mg to 20 mg is recommended approximately 30 minutes prior to sexual activity.
• For BPH, a daily dose of 5 mg is typical.

Side Effects

• Common effects include headache, facial flushing, digestive issues (nausea, diarrhea), dizziness, muscle pain, and backache.
• Rarely, severe side effects like sudden vision or hearing loss may occur.

Dapoxetine

Dapoxetine, sold under the brand name Priligy, is a medication aimed at treating premature ejaculation in men.

Mechanism of Action

• Falls under selective serotonin reuptake inhibitors (SSRIs).
• Increases serotonin availability in the brain by slowing its reuptake.
• Heightened serotonin governs ejaculation control, extending time to ejaculation.

Indications

• Primarily indicated for men dealing with premature ejaculation.
• Target demographic includes men aged 18 to 64 years.

Onset of Action

• A quick effect is experienced 1 to 2 hours after intake.

Duration of Action

• Effects typically last 4 to 24 hours, varying with dosage and individual response.

Dosage

• Usual dosage ranges from 30 mg to 60 mg, taken as needed, starting at 30 mg for initial use.
• Physicians may adjust based on patient response.

Side Effects

• Commonly reported side effects consist of dizziness, headache, nausea, fatigue, dry mouth, and drowsiness.
• Uncommon effects may include hot flashes, increased anxiety, behavioral changes, or sexual function alterations.

Contraindications

• Not for use in patients with severe hepatic/renal dysfunction, serious cardiac issues, epilepsy, or bipolar disorder.
• Avoid alcohol, which could heighten side effect risks.