Sunrise Extra Super Tadarise 100 tabs (40 + 60 mg/tab)

Tadalafil – Cialis

Tadalafil is an effective erectile dysfunction treatment, classified as a phosphodiesterase type 5 (PDE5) inhibitor. Marketed under the names Cialis and Adcirca, it also addresses pulmonary arterial hypertension.

Characteristics of Tadalafil:

Mechanism of Action

• Tadalafil inhibits the enzyme PDE5, preventing the breakdown of cyclic guanosine monophosphate (cGMP).
• It enhances cGMP levels following nitric oxide (NO) release during sexual arousal.
• This action promotes relaxation of penile blood vessel smooth muscles, facilitating erections.

Indications

• Primarily for treating erectile dysfunction.
• Also effective for managing benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension via Adcirca.

Onset of Action

• Acts rapidly, typically within 30 minutes to 1 hour.

Duration of Action

• Effects last up to 36 hours, earning it the nickname “weekend pill.”
• Allows men to maintain an erection when sexually stimulated during this period.

Dosage

• Recommended dosage for erectile dysfunction is 10 mg or 20 mg, taken approximately 30 minutes before sexual activity.
• A daily dose of 5 mg is common for BPH.

Side Effects

• Common effects include headache, facial flushing, indigestion, dizziness, muscle pain, and backache.
• Serious risks such as sudden vision or hearing loss are rare but possible.

Dapoxetine

Dapoxetine is designed to treat premature ejaculation in men, marketed as Priligy.

Characteristics of Dapoxetine:

Mechanism of Action

• Dapoxetine is a selective serotonin reuptake inhibitor (SSRI).
• It enhances serotonin availability by slowing its reuptake, improving ejaculation control.
• This results in a longer time to ejaculation.

Indications

• Primarily for treating premature ejaculation in men aged 18 to 64.

Onset of Action

• Action begins approximately 1 to 2 hours post-ingestion.

Duration of Action

• Effects may last between 4 to 24 hours, contingent on dosage and patient response.

Dosage

• Standard doses range from 30 mg to 60 mg, taken as required.
• The starting dose is typically 30 mg, adjustable based on response.

Side Effects

• Common side effects include dizziness, headache, nausea, drowsiness, fatigue, and dry mouth.
• Rarely, symptoms like hot flashes, increased anxiety, or sexual function changes may arise.

Contraindications

• Contraindicated in patients with severe hepatic or renal issues, heart problems, epilepsy, bipolar disorder, or on MAO inhibitors.
• Combining with alcohol is not advisable due to heightened side effect risk.